Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects

BACKGROUND: Histone H3 methylation at lysine 9 (H3K9) is a conserved epigenetic signal, mediating heterochromatin formation by trimethylation, and transcriptional silencing by dimethylation. Defective GLP (Ehmt1) and G9a (Ehmt2) histone lysine methyltransferases, involved in mono and dimethylation o...

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Détails bibliographiques
Publié dans:Mol Autism
Auteurs principaux: Balan, Shabeesh, Iwayama, Yoshimi, Maekawa, Motoko, Toyota, Tomoko, Ohnishi, Tetsuo, Toyoshima, Manabu, Shimamoto, Chie, Esaki, Kayoko, Yamada, Kazuo, Iwata, Yasuhide, Suzuki, Katsuaki, Ide, Masayuki, Ota, Motonori, Fukuchi, Satoshi, Tsujii, Masatsugu, Mori, Norio, Shinkai, Yoichi, Yoshikawa, Takeo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233047/
https://ncbi.nlm.nih.gov/pubmed/25400900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-5-49
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