RNA-seq profiling of a radiation resistant and radiation sensitive prostate cancer cell line highlights opposing regulation of DNA repair and targets for radiosensitization

BACKGROUND: Radiotherapy is a chosen treatment option for prostate cancer patients and while some tumours respond well, up to 50% of patients may experience tumour recurrence. Identification of functionally relevant predictive biomarkers for radioresponse in prostate cancer would enable radioresista...

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Publicado en:BMC Cancer
Autores principales: Young, Arabella, Berry, Rachael, Holloway, Adele F, Blackburn, Nicholas B, Dickinson, Joanne L, Skala, Marketa, Phillips, Jessica L, Brettingham-Moore, Kate H
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233036/
https://ncbi.nlm.nih.gov/pubmed/25369795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-808
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