Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicity.
Attenuated Salmonella are useful oral vaccine vectors capable of carrying multiple heterologous antigen genes, but optimal expression of foreign antigens has not yet been achieved. We hypothesized that Salmonella phoP-activated genes, which are transcriptionally activated within antigen-processing m...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42327/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2904 |
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