Bile acids are essential for porcine enteric calicivirus replication in association with down-regulation of signal transducer and activator of transcription 1

A porcine enteric calicivirus (PEC), strain Cowden in the family Caliciviridae (genus Sapovirus), can be propagated in a continuous cell line, LLC-PK cells, but only in the presence of an intestinal content fluid filtrate from gnotobiotic pigs. This cell culture system is presently the only in vitro...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Chang, Kyeong-Ok, Sosnovtsev, Stanislav V., Belliot, Gaël, Kim, Yunjeong, Saif, Linda J., Green, Kim Y.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423264/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15161971/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401126101
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