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Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites

Among potential new targets for antimalarial chemotherapy are Plasmodium falciparum cysteine proteases, known as falcipains. Falcipain-2 and falcipain-3 are food vacuole hemoglobinases that may have additional functions. The function of falcipain-1 remains uncertain. To better characterize the role...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sijwali, Puran S., Kato, Kentaro, Seydel, Karl B., Gut, Jiri, Lehman, Julie, Klemba, Michael, Goldberg, Daniel E., Miller, Louis H., Rosenthal, Philip J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423262/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15166288/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402738101
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