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Loss of EP2 Receptor Subtype in Colonic Cells Compromise Epithelial Barrier Integrity by Altering Claudin-4

Prostaglandin E(2) (PGE(2)) is a bioactive lipid mediator that exerts its biological function through interaction with four different subtypes of E-Prostanoid receptor namely EP1, EP2, EP3 and EP4. It has been known that EP2 receptor is differentially over-expressed in the epithelia of inflamed huma...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lejeune, Manigandan, Moreau, France, Chadee, Kris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232557/
https://ncbi.nlm.nih.gov/pubmed/25396731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113270
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