Sub-cellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas

We identified a Cu accumulating structure with a dynamic role in intracellular Cu homeostasis. During Zn limitation, Chlamydomonas reinhardtii hyperaccumulated Cu, dependent on the nutritional Cu sensor CRR1, but was functionally Cu-deficient. Visualization of intracellular Cu revealed major Cu accu...

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Publicado en:Nat Chem Biol
Autores principales: Hong-Hermesdorf, Anne, Miethke, Marcus, Gallaher, Sean D, Kropat, Janette, Dodani, Sheel C, Chan, Jefferson, Barupala, Dulmini, Domaille, Dylan W, Shirasaki, Dyna I, Loo, Joseph A, Weber, Peter K, Pett-Ridge, Jennifer, Stemmler, Timothy L, Chang, Christopher J, Merchant, Sabeeha S
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232477/
https://ncbi.nlm.nih.gov/pubmed/25344811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1662
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