A New Recombinant BCG Vaccine Induces Specific Th17 and Th1 Effector Cells with Higher Protective Efficacy against Tuberculosis

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) that is a major public health problem. The vaccine used for TB prevention is Mycobacterium bovis bacillus Calmette-Guérin (BCG), which provides variable efficacy in protecting against pulmonary TB among adults. Con...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: da Costa, Adeliane Castro, Costa-Júnior, Abadio de Oliveira, de Oliveira, Fábio Muniz, Nogueira, Sarah Veloso, Rosa, Joseane Damaceno, Resende, Danilo Pires, Kipnis, André, Junqueira-Kipnis, Ana Paula
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232451/
https://ncbi.nlm.nih.gov/pubmed/25398087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112848
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