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Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein
Aurora-A kinase is necessary for centrosome maturation, for assembly and maintenance of a bipolar spindle, and for proper chromosome segregation during cell division. Aurora-A is an oncogene that is overexpressed in multiple human cancers. Regulation of kinase activity apparently depends on phosphor...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC423245/ https://ncbi.nlm.nih.gov/pubmed/15173575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402966101 |
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