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N-Activated β-Lactams as Versatile Reagents for Acyl Carrier Protein Labeling

Acyl carrier proteins are critical components of fatty acid and polyketide biosynthesis. Their primary function is to shuttle intermediates between active sites via a covalently bound phosphopantetheine arm. Small molecules capable of acylating this prosthetic group will provide a simple and reversi...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Prasad, Gitanjeli, Amoroso, Jon W., Borketey, Lawrence S., Schnarr, Nathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232301/
https://ncbi.nlm.nih.gov/pubmed/22293823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob06846j
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