Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes

Eradication of Mycobacterium tuberculosis (MTB) infection requires daily administration of combinations of rifampin (RIF), isoniazid [isonicotinylhydrazine (INH)], pyrazinamide, and ethambutol, among other drug therapies. To facilitate and optimize MTB therapeutic selections, a mononuclear phagocyte...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Edagwa, Benson J., Guo, Dongwei, Puligujja, Pavan, Chen, Han, McMillan, JoEllyn, Liu, Xinming, Gendelman, Howard E., Narayanasamy, Prabagaran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2014
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232285/
https://ncbi.nlm.nih.gov/pubmed/25122556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-255786
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