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Improved Pharmacokinetics of Sumatriptan With Breath Powered™ Nasal Delivery of Sumatriptan Powder

OBJECTIVES.—: The purpose of this study was to directly compare the pharmacokinetic (PK) profile of 22-mg sumatriptan powder delivered intranasally with a novel Breath Powered™ device (11 mg in each nostril) vs a 20-mg sumatriptan liquid nasal spray, a 100-mg oral tablet, and a 6-mg subcutaneous inj...

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Detalhes bibliográficos
Publicado no:Headache
Main Authors: Obaidi, Mohammad, Offman, Elliot, Messina, John, Carothers, Jennifer, Djupesland, Per G, Mahmoud, Ramy A
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232272/
https://ncbi.nlm.nih.gov/pubmed/23992438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/head.12167
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