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Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells

PURPOSE: Detached breast tumor cells produce dynamic microtubule protrusions that promote reattachment of cells and are termed tubulin microtentacles (McTNs) due to their mechanistic distinctions from actin-based filopodia/invadopodia and tubulin-based cilia. McTNs are enriched with vimentin and det...

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Bibliographische Detailangaben
Veröffentlicht in:Breast Cancer Res Treat
Hauptverfasser: Yoon, Jennifer R., Whipple, Rebecca A., Balzer, Eric M., Cho, Edward H., Matrone, Michael A., Peckham, Michelle, Martin, Stuart S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232214/
https://ncbi.nlm.nih.gov/pubmed/21069453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-1239-7
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