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Lentivirus Delivery of IL-10 to Promote and Sustain Macrophage Polarization Towards an Anti-Inflammatory Phenotype

Gene delivery from biomaterials can create an environment that promotes and guides tissue formation. However, the immune response induced upon biomaterial implantation can be detrimental to tissue regeneration. Macrophages play a central role in mediating early phases of this response, and functiona...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Boehler, R.M., Kuo, R., Shin, S., Goodman, A.G., Pilecki, M.A., Leonard, J.N., Shea, L.D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232188/
https://ncbi.nlm.nih.gov/pubmed/24375008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25175
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