Increase in DNA vaccine efficacy by virosome delivery and co-expression of a cytolytic protein

The potential of DNA vaccines has not been realised due to suboptimal delivery, poor antigen expression and the lack of localised inflammation, essential for antigen presentation and an effective immune response to the immunogen. Initially, we examined the delivery of a DNA vaccine encoding a model...

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發表在:Clin Transl Immunology
Main Authors: Gargett, Tessa, Grubor-Bauk, Branka, Miller, Darren, Garrod, Tamsin, Yu, Stanley, Wesselingh, Steve, Suhrbier, Andreas, Gowans, Eric J
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2014
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232068/
https://ncbi.nlm.nih.gov/pubmed/25505966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2014.13
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