Objective validation of central sensitization in the rat UVB and heat rekindling model

BACKGROUND: The UVB and heat rekindling (UVB/HR) model shows potential as a translatable inflammatory pain model. However, the occurrence of central sensitization in this model, a fundamental mechanism underlying chronic pain, has been debated. Face, construct and predictive validity are key requisi...

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Bibliographic Details
Published in:Eur J Pain
Main Authors: Weerasinghe, NS, Lumb, BM, Apps, R, Koutsikou, S, Murrell, JC
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
New Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232048/
https://ncbi.nlm.nih.gov/pubmed/24590815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/j.1532-2149.2014.00469.x
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