Establishment and operation of a Good Manufacturing Practice-compliant allogeneic Epstein-Barr virus (EBV)-specific cytotoxic cell bank for the treatment of EBV-associated lymphoproliferative disease

Epstein-Barr virus (EBV) is associated with several malignancies, including post-transplant lymphoproliferative disorder (PTLD). Conventional treatments for PTLD are often successful, but risk organ rejection and cause significant side effects. EBV-specific cytotoxic T lymphocytes (CTLs) generated i...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Vickers, Mark A, Wilkie, Gwen M, Robinson, Nicolas, Rivera, Nadja, Haque, Tanzina, Crawford, Dorothy H, Barry, Jacqueline, Fraser, Neil, Turner, David M, Robertson, Victoria, Dyer, Phil, Flanagan, Peter, Newlands, Helen R, Campbell, John, Turner, Marc L
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232001/
https://ncbi.nlm.nih.gov/pubmed/25066775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13051
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