Total and unbound darunavir pharmacokinetics in pregnant women infected with HIV-1: results of a study of darunavir/ritonavir 600/100 mg administered twice daily

OBJECTIVES: Antiretroviral therapy during pregnancy is recommended to reduce the risk of mother-to-child transmission of HIV and for maternal care management. Physiological changes during pregnancy can affect pharmacokinetics, potentially altering pharmacological activity. We therefore evaluated the...

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Detalhes bibliográficos
Publicado no:HIV Med
Main Authors: Zorrilla, CD, Wright, R, Osiyemi, OO, Yasin, S, Baugh, B, Brown, K, Coate, B, Verboven, P, Mrus, J, Falcon, R, Kakuda, TN
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231999/
https://ncbi.nlm.nih.gov/pubmed/23731450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hiv.12047
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