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Intrastromal Delivery of Bevacizumab Using Microneedles to Treat Corneal Neovascularization

PURPOSE. This study tested the hypothesis that highly targeted intrastromal delivery of bevacizumab using coated microneedles allows dramatic dose sparing compared with subconjunctival and topical delivery for treatment of corneal neovascularization. METHODS. Stainless steel microneedles 400 μm in l...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Kim, Yoo C., Grossniklaus, Hans E., Edelhauser, Henry F., Prausnitz, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231993/
https://ncbi.nlm.nih.gov/pubmed/25212779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15257
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