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Multiple interactions between regulatory regions are required to stabilize an active chromatin hub

The human β-globin locus control region (LCR) is required for the maintenance of an open chromatin configuration of the locus. It interacts with the genes and the hypersensitive regions flanking the locus to form an active chromatin hub (ACH) transcribing the genes. Proper developmental control of g...

詳細記述

保存先:
書誌詳細
主要な著者: Patrinos, George P., de Krom, Mariken, de Boer, Ernie, Langeveld, An, Imam, A.M. Ali, Strouboulis, John, de Laat, Wouter, Grosveld, Frank G.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC423198/
https://ncbi.nlm.nih.gov/pubmed/15198986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.289704
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