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gp130 and c-Kit signalings synergize for ex vivo expansion of human primitive hemopoietic progenitor cells.

gp130, a signal-transducing receptor component of interleukin 6 (IL-6), associates with an IL-6 and IL-6 receptor (IL-6) complex and transduces signals. To examine the role of gp130 signaling in the expansion of human hemopoietic progenitor cells, we tested the effects of a recombinant soluble human...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Sui, X, Tsuji, K, Tanaka, R, Tajima, S, Muraoka, K, Ebihara, Y, Ikebuchi, K, Yasukawa, K, Taga, T, Kishimoto, T
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42318/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7535932/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2859
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