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Live-cell quantitative imaging of proteome degradation by stimulated Raman scattering

Protein degradation is a regulatory process essential to cell viability, and its dysfunction is implicated in many diseases such as aging and neurodegeneration. Here we report stimulated Raman scattering microscopy coupled with metabolic labeling of (13)C-phenylalanine to visualize protein degradati...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Shen, Yihui, Xu, Fang, Wei, Lu, Hu, Fanghao, Min, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231775/
https://ncbi.nlm.nih.gov/pubmed/24737659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310725
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