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Live-cell quantitative imaging of proteome degradation by stimulated Raman scattering

Protein degradation is a regulatory process essential to cell viability, and its dysfunction is implicated in many diseases such as aging and neurodegeneration. Here we report stimulated Raman scattering microscopy coupled with metabolic labeling of (13)C-phenylalanine to visualize protein degradati...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Shen, Yihui, Xu, Fang, Wei, Lu, Hu, Fanghao, Min, Wei
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231775/
https://ncbi.nlm.nih.gov/pubmed/24737659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310725
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