HSP90α plays an important role in piRNA biogenesis and retrotransposon repression in mouse

HSP90, found in all kingdoms of life, is a major chaperone protein regulating many client proteins. We demonstrated that HSP90α, one of two paralogs duplicated in vertebrates, plays an important role in the biogenesis of fetal PIWI-interacting RNAs (piRNA), which act against the transposon activitie...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Ichiyanagi, Tomoko, Ichiyanagi, Kenji, Ogawa, Ayako, Kuramochi-Miyagawa, Satomi, Nakano, Toru, Chuma, Shinichiro, Sasaki, Hiroyuki, Udono, Heiichiro
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231750/
https://ncbi.nlm.nih.gov/pubmed/25262350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku881
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