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Loss of Vacuolar H(+)-ATPase Activity in Organelles Signals Ubiquitination and Endocytosis of the Yeast Plasma Membrane Proton pump Pma1p

Yeast mutants lacking the intracellular V-ATPase proton pump (vma mutants) have reduced levels of the Pma1p proton pump at the plasma membrane and increased levels in organelles including the vacuolar lumen. We examined the mechanism and physiological consequences of Pma1p mislocalization. Pma1p is...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Smardon, Anne M., Kane, Patricia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231704/
https://ncbi.nlm.nih.gov/pubmed/25271159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574442
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