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Loss of Vacuolar H(+)-ATPase Activity in Organelles Signals Ubiquitination and Endocytosis of the Yeast Plasma Membrane Proton pump Pma1p

Yeast mutants lacking the intracellular V-ATPase proton pump (vma mutants) have reduced levels of the Pma1p proton pump at the plasma membrane and increased levels in organelles including the vacuolar lumen. We examined the mechanism and physiological consequences of Pma1p mislocalization. Pma1p is...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Smardon, Anne M., Kane, Patricia M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231704/
https://ncbi.nlm.nih.gov/pubmed/25271159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574442
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