Adipocyte Lipolysis-stimulated Interleukin-6 Production Requires Sphingosine Kinase 1 Activity

Adipocyte lipolysis can increase the production of inflammatory cytokines such as interleukin-6 (IL-6) that promote insulin resistance. However, the mechanisms that link lipolysis with inflammation remain elusive. Acute activation of β(3)-adrenergic receptors (ADRB3) triggers lipolysis and up-regula...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Wenliang, Mottillo, Emilio P., Zhao, Jiawei, Gartung, Allison, VanHecke, Garrett C., Lee, Jen-Fu, Maddipati, Krishna R., Xu, Haiyan, Ahn, Young-Hoon, Proia, Richard L., Granneman, James G., Lee, Menq-Jer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231693/
https://ncbi.nlm.nih.gov/pubmed/25253697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601096
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