A Role for Stefin B (Cystatin B) in Inflammation and Endotoxemia

Stefin B (cystatin B) is an endogenous cysteine cathepsin inhibitor, and the loss-of-function mutations in the stefin B gene were reported in patients with Unverricht-Lundborg disease (EPM1). In this study we demonstrated that stefin B-deficient (StB KO) mice were significantly more sensitive to the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Maher, Katarina, Jerič Kokelj, Barbara, Butinar, Miha, Mikhaylov, Georgy, Manček-Keber, Mateja, Stoka, Veronika, Vasiljeva, Olga, Turk, Boris, Grigoryev, Sergei A., Kopitar-Jerala, Nataša
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231653/
https://ncbi.nlm.nih.gov/pubmed/25288807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.609396
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