In search of rare variants: Preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes

Whole genome sequencing was completed on 1,325 individuals from 602 families, identifying 27 million autosomal variants. Genetic association tests were conducted for those individuals who had been assessed for one or more of 17 endophenotypes (N range = 802–1,185). No significant associations were f...

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Publicado no:Psychophysiology
Main Authors: VRIEZE, SCOTT I., MALONE, STEPHEN M., VAIDYANATHAN, UMA, KWONG, ALAN, KANG, HYUN MIN, ZHAN, XIAOWEI, FLICKINGER, MATTHEW, IRONS, DANIEL, JUN, GOO, LOCKE, ADAM E., PISTIS, GIORGIO, PORCU, ELEONORA, LEVY, SHAWN, MYERS, RICHARD M., OETTING, WILLIAM, MCGUE, MATT, ABECASIS, GONCALO, IACONO, WILLIAM G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231480/
https://ncbi.nlm.nih.gov/pubmed/25387710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/psyp.12350
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