Vectorial secretion of interleukin-8 mediates autocrine signalling in intestinal epithelial cells via apically located CXCR1

BACKGROUND: In the intestinal mucosa, several adaptations of TLR signalling have evolved to avoid chronic inflammatory responses to the presence of commensal microbes. Here we investigated whether polarized monolayers of intestinal epithelial cells might regulate inflammatory responses by secreting...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Rossi, Oriana, Karczewski, Jurgen, Stolte, Ellen H, Brummer, Robert J M, van Nieuwenhoven, Michiel A, Meijerink, Marjolein, van Neerven, Joost R J, van Ijzendoorn, Sven C D, van Baarlen, Peter, Wells, Jerry M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231470/
https://ncbi.nlm.nih.gov/pubmed/24164922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-431
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