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Reconstruction of large-scale regulatory networks based on perturbation graphs and transitive reduction: improved methods and their evaluation
BACKGROUND: The data-driven inference of intracellular networks is one of the key challenges of computational and systems biology. As suggested by recent works, a simple yet effective approach for reconstructing regulatory networks comprises the following two steps. First, the observed effects induc...
Enregistré dans:
| Publié dans: | BMC Syst Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231426/ https://ncbi.nlm.nih.gov/pubmed/23924435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-73 |
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