Growth hormone receptor signaling is dispensable for HSC function and aging

Growth hormone receptor (Ghr) signaling is important in a wide variety of cellular processes including aging; however, the role of Ghr signaling in hematopoietic stem cell (HSC) biology remains unexplored. Within the hematopoietic system, Ghr is expressed in a highly HSC-specific manner and is signi...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Stewart, Morag H., Gutierrez-Martinez, Paula, Beerman, Isabel, Garrison, Brian, Gallagher, Emily J., LeRoith, Derek, Rossi, Derrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231418/
https://ncbi.nlm.nih.gov/pubmed/25274507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-575308
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