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Absence of the TAP2 Human Recombination Hotspot in Chimpanzees

Recent experiments using sperm typing have demonstrated that, in several regions of the human genome, recombination does not occur uniformly but instead is concentrated in “hotspots” of 1–2 kb. Moreover, the crossover asymmetry observed in a subset of these has led to the suggestion that hotspots ma...

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Autors principals: Ptak, Susan E, Roeder, Amy D, Stephens, Matthew, Gilad, Yoav, Pääbo, Svante, Przeworski, Molly
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC423135/
https://ncbi.nlm.nih.gov/pubmed/15208713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020155
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