rpS6 regulates blood–testis barrier dynamics through Akt-mediated effects on MMP-9

Mammalian target of rapamycin complex 1 (mTORC1) is an emerging regulator of blood–tissue barriers that utilizes ribosomal protein S6 (rpS6) as the downstream signaling molecule. To explore the role of rpS6 in blood–testis barrier (BTB) function, a constitutively active quadruple rpS6 phosphomimetic...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Mok, Ka-Wai, Mruk, Dolores D., Cheng, C. Yan
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231304/
https://ncbi.nlm.nih.gov/pubmed/25217631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.152231
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