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Possible Contribution of Taurine to Distorted Glucagon Secretion in Intra-Islet Insulin Deficiency: A Metabolome Analysis Using a Novel α-Cell Model of Insulin-Deficient Diabetes

Glycemic instability is a serious problem in patients with insulin-deficient diabetes, and it may be due in part to abnormal endogenous glucagon secretion. However, the intracellular metabolic mechanism(s) involved in the aberrant glucagon response under the condition of insulin deficiency has not y...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bessho, Megumi, Murase-Mishiba, Yuko, Imagawa, Akihisa, Terasaki, Jungo, Hanafusa, Toshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231115/
https://ncbi.nlm.nih.gov/pubmed/25393115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113254
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