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Dimethyloxalylglycine Prevents Bone Loss in Ovariectomized C57BL/6J Mice through Enhanced Angiogenesis and Osteogenesis

Hypoxia-inducible factor 1-α (HIF-1α) plays a critical role in angiogenesis-osteogenesis coupling during bone development and bone regeneration. Previous studies have shown that 17β-estradiol activates the HIF-1α signaling pathway and that mice with conditional activation of the HIF-1α signaling pat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Peng, Jia, Lai, Zuo Gui, Fang, Zhang Lian, Xing, Shen, Hui, Kang, Hao, Chen, Jin, Qi, Qi, Zhou, Shen, Wang Jin, Dong, Qian Nian, Bing, Zhou Han, Fu, Deng Lian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231053/
https://ncbi.nlm.nih.gov/pubmed/25394221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112744
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