Endogenously opsonized particles divert prostanoid action from lethal to protective in models of experimental endotoxemia.

We report that, in rats, the lethal consequences of high-dose endotoxin challenge are exacerbated by the intravascular administration of prostaglandin E1 but attenuated by the intravascular administration of endocytosable particles. This protection is mediated by opsonins. Nonopsonizable particles w...

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Main Authors: Eierman, D F, Yagami, M, Erme, S M, Minchey, S R, Harmon, P A, Pratt, K J, Janoff, A S
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC42309/
https://ncbi.nlm.nih.gov/pubmed/7708730
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