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Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation

The pathways driving desmosome and adherens junction assembly are temporally and spatially coordinated, but how they are functionally coupled is poorly understood. Here we show that the Armadillo protein plakophilin 3 (Pkp3) mediates both desmosome assembly and E-cadherin maturation through Rap1 GTP...

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Publicat a:Mol Biol Cell
Autors principals: Todorovic´, Viktor, Koetsier, Jennifer L., Godsel, Lisa M., Green, Kathleen J.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230782/
https://ncbi.nlm.nih.gov/pubmed/25208567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-05-0968
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