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Prophylactic erythropoietin exacerbates ventilation-induced lung inflammation and injury in preterm lambs

Ventilation-induced lung injury (VILI) of preterm neonates probably contributes to the pathogenesis of bronchopulmonary dysplasia (BPD). Erythropoietin (EPO) has been suggested as a therapy for BPD. The aim of this study was to determine whether prophylactic administration of EPO reduces VILI in pre...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Polglase, Graeme R, Barton, Samantha K, Melville, Jacqueline M, Zahra, Valerie, Wallace, Megan J, Siew, Melissa L, Tolcos, Mary, Moss, Timothy J M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230774/
https://ncbi.nlm.nih.gov/pubmed/24591575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.270348
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