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Hydroxyl fasudil, an inhibitor of Rho signaling, improves erectile function in diabetic rats: a role for neuronal ROCK

INTRODUCTION: The pathogenesis of diabetic erectile dysfunction (ED) includes neuropathy, but the molecular basis for neurogenic ED is incompletely understood. The RhoA/ROCK pathway has been implicated in diabetic neuropathy and in ED, but its role in diabetic neurogenic ED is not known. AIMS: The a...

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Bibliographische Detailangaben
Veröffentlicht in:J Sex Med
Hauptverfasser: Sezen, Sena F., Lagoda, Gwen, Musicki, Biljana, Burnett, Arthur L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230280/
https://ncbi.nlm.nih.gov/pubmed/24919622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jsm.12613
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