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Direct fluorination of phenolsulfonphthalein: a method for synthesis of positron-emitting indicators for in vivo pH measurement

We report a reaction of direct electrophilic fluorination of phenolsulfonphthalein at mild conditions. This reaction affords the synthesis of novel positron-emitting (18)F-labeled pH indicators. These compounds are useful for non-invasive in vivo pH measurement in biological objects.

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Bibliografski detalji
Izdano u:Cell Biochem Biophys
Glavni autori: Kachur, Alexander V., Popov, Anatoliy V., Karp, Joel S., Delikatny, E. James
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230276/
https://ncbi.nlm.nih.gov/pubmed/22790882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-012-9390-x
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