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Synergistic Action of Cord Factor and Mycobacterial Sulfatides on Mitochondria

The mechanism of a synergistic toxicity of 6,6′-dimycoloyl-α,α′-d-trehalose (cord factor) and 2,3,6,6′-tetraacyl-α,α′-d-trehalose 2′-sulfate (sulfolipid I) for mice was studied. Sulfolipid I was entirely nontoxic, but it markedly accelerated the lethal toxicity of cord factor for mice. In vivo, sulf...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Kato, Masahiko, Goren, Mayer B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4214779/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.10.4.733-741.1974
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