Benzodiazepine receptors mediate regional blood flow changes in the living human brain.

We studied the effects of a high-affinity gamma-aminobutyric acid (GABA)-benzodiazepine-receptor agonist (lorazepam) and an antagonist (flumazenil) in humans, using H2(15)O positron-emission tomography. Administration of lorazepam to healthy volunteers caused time- and dose-dependent reductions in r...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Matthew, E, Andreason, P, Pettigrew, K, Carson, R E, Herscovitch, P, Cohen, R, King, C, Johanson, C E, Greenblatt, D J, Paul, S M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708722/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2775
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