Loss of histone H4K20 trimethylation predicts poor prognosis in breast cancer and is associated with invasive activity

INTRODUCTION: Loss of histone H4 lysine 20 trimethylation (H4K20me3) is associated with multiple cancers, but its role in breast tumors is unclear. In addition, the pathological effects of global reduction in H4K20me3 remain mostly unknown. Therefore, a major goal of this study was to elucidate the...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Yokoyama, Yuhki, Matsumoto, Ayaka, Hieda, Miki, Shinchi, Yoshimi, Ogihara, Eri, Hamada, Mai, Nishioka, Yu, Kimura, Hiroshi, Yoshidome, Katsuhide, Tsujimoto, Masahiko, Matsuura, Nariaki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229880/
https://ncbi.nlm.nih.gov/pubmed/24953066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3681
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