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Efficient apoptosis and necrosis induction by proteasome inhibitor: bortezomib in the DLD-1 human colon cancer cell line

The inhibition of the 26S proteasome evokes endoplasmic reticulum stress, which has been shown to be implicated in the antitumoral effects of proteasome inhibitors. The cellular and molecular effects of the proteasome inhibitor—bortezomib—on human colon cancer cells are as yet poorly characterized....

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Bibliografiske detaljer
Udgivet i:Mol Cell Biochem
Main Authors: Krętowski, Rafał, Stypułkowska, Anna, Cechowska-Pasko, Marzanna
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229651/
https://ncbi.nlm.nih.gov/pubmed/25292312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-014-2216-y
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