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Dopamine Modulation of GABAergic Function Enables Network Stability and Input Selectivity for Sustaining Working Memory in a Computational Model of the Prefrontal Cortex

Dopamine modulation of GABAergic transmission in the prefrontal cortex (PFC) is thought to be critical for sustaining cognitive processes such as working memory and decision-making. Here, we developed a neurocomputational model of the PFC that includes physiological features of the facilitatory acti...

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Bibliografiske detaljer
Udgivet i:Neuropsychopharmacology
Main Authors: Lew, Sergio E, Tseng, Kuei Y
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229578/
https://ncbi.nlm.nih.gov/pubmed/24975022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.160
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