Effects of Genetic Deletion of Endogenous Opioid System Components on the Reinstatement of Cocaine-Seeking Behavior in Mice

The repeated cycles of cessation of consumption and relapse remain the major clinical concern in treating drug addiction. The endogenous opioid system is a crucial component of the reward circuit that participates in the adaptive changes leading to relapse in the addictive processes. We have used ge...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Gutiérrez-Cuesta, Javier, Burokas, Aurelijus, Mancino, Samantha, Kummer, Sami, Martín-García, Elena, Maldonado, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229567/
https://ncbi.nlm.nih.gov/pubmed/24943644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.149
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