Serum Peak Sulfamethoxazole Concentrations Demonstrate Difficulty in Achieving a Target Range: A Retrospective Cohort Study

OBJECTIVES: Trimethoprim (TMP)/sulfamethoxazole (SMX) has consistently demonstrated great interindividual variability. Therapeutic drug monitoring may be used to optimize dosing. Optimal peak SMX concentration has been proposed as 100 to 150 μg/mL. The objective of our work was to determine the succ...

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Detalhes bibliográficos
Publicado no:Curr Ther Res Clin Exp
Main Authors: Dao, Bao D., Barreto, Jason N., Wolf, Robert C., Dierkhising, Ross A., Plevak, Matthew F., Tosh, Pritish K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229511/
https://ncbi.nlm.nih.gov/pubmed/25408788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2014.08.003
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