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Transfusion of stored blood impairs host defenses against Gram-negative pathogens in mice

BACKGROUND: Although human red blood cell (RBC) units may be refrigerator stored for up to 42 days, transfusion of older RBCs acutely delivers a large bolus of iron to mononuclear phagocytes. Similarly, iron dextran circulates in plasma for hours to days and is progressively cleared by mononuclear p...

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Detalhes bibliográficos
Publicado no:Transfusion
Main Authors: Prestia, Kevin, Bandyopadhyay, Sheila, Slate, Andrea, Francis, Richard O., Francis, Kevin P., Spitalnik, Steven L., Fidock, David A., Brittenham, Gary M., Hod, Eldad A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229414/
https://ncbi.nlm.nih.gov/pubmed/24840185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.12712
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