β-Adrenergic Receptor-Mediated Cardiac Contractility is Inhibited via Vasopressin Type 1A-Receptor-Dependent Signaling

BACKGROUND: Enhanced arginine vasopressin (AVP) levels are associated with increased mortality during end-stage human heart failure (HF), and cardiac AVP type 1A receptor (V1AR) expression becomes increased. Additionally, mice with cardiac-restricted V1AR overexpression develop cardiomyopathy and de...

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發表在:Circulation
Main Authors: Tilley, Douglas G., Zhu, Weizhong, Myers, Valerie D., Barr, Larry A., Gao, Erhe, Li, Xue, Song, Jianliang, Carter, Rhonda L., Makarewich, Catherine A., Yu, Daohai, Troupes, Constantine D., Grisanti, Laurel A., Coleman, Ryan C., Koch, Walter J., Houser, Steven R., Cheung, Joseph Y., Feldman, Arthur M.
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229385/
https://ncbi.nlm.nih.gov/pubmed/25205804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.010434
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