β-Adrenergic Receptor-Mediated Cardiac Contractility is Inhibited via Vasopressin Type 1A-Receptor-Dependent Signaling

BACKGROUND: Enhanced arginine vasopressin (AVP) levels are associated with increased mortality during end-stage human heart failure (HF), and cardiac AVP type 1A receptor (V1AR) expression becomes increased. Additionally, mice with cardiac-restricted V1AR overexpression develop cardiomyopathy and de...

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Publicat a:Circulation
Autors principals: Tilley, Douglas G., Zhu, Weizhong, Myers, Valerie D., Barr, Larry A., Gao, Erhe, Li, Xue, Song, Jianliang, Carter, Rhonda L., Makarewich, Catherine A., Yu, Daohai, Troupes, Constantine D., Grisanti, Laurel A., Coleman, Ryan C., Koch, Walter J., Houser, Steven R., Cheung, Joseph Y., Feldman, Arthur M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229385/
https://ncbi.nlm.nih.gov/pubmed/25205804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.010434
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