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Use of Independent Component Analysis to Improve Signal to Noise Ratio in Multi-probe Fluorescence Microscopy

In conventional multi-probe fluorescence microscopy, narrow bandwidth filters on detectors are used to avoid bleed-through artifacts between probes. The limited bandwidth reduces the signal-to-noise ratio (SNR) of the detection, often severely compromising one or more channels. Herein, we describe a...

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Bibliographic Details
Published in:J Microsc
Main Authors: Dao, Lam, Lucotte, Bertrand, Glancy, Brian, Chang, Lin-Ching, Hsu, Li-Yueh, Balaban, Robert S
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229364/
https://ncbi.nlm.nih.gov/pubmed/25159193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jmi.12167
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